After earning his Biology Bachelor's degree in Turkey, Duhan was awarded a Fulbright Scholarship to study Chemical Engineering at Rensselaer Polytechnic Institute (USA). He completed his PhD in 2019 at the University of Trento, Italy, under the supervision of Sheref Mansy and also worked with Jack Szostak at Harvard University during this time.

Following a brief postdoctoral position at Yale University, he joined the Bayley group in 2022 as a postdoctoral fellow, supported by HFSP Long-term and Marie-Curie Fellowships. His research focuses on single-molecule chemistry and functional nanopores for catalysis, building on his prior work in chemical origins-of-life, synthetic biology, artificial cells, and in vitro evolution.